DNA methylation at CG sites is important for gene regulation and embryonic development.In mouse oocytes, de novo CG methylation requires preceding transcription-coupled histone mark H3K36me3 and is mediated by a DNA methyltransferase DNMT3A.DNMT3A has a PWWP domain, which recognizes H3K36me2/3, and heterozygous mutations in this domain, including D
A novel photonic approach to generating a frequency-quadrupled millimeter-wave (mm-wave) signal with a tunable phase shift is proposed and demonstrated.Two second-order optical sidebands are generated by using a Mach-Zehnder modulator (MZM) that is biased at the maximum transmission point and an optical notch filter.A polarization-maintaining fiber
The aim of this paper is to find and examine iphone xr price calgary effective technological methods through which, if well-applied, organizations develop fast and thus reach the peak of success.This study aims to identify strategies that help to transfer traditional management system to a modern smart one.The research adopts both descriptive and a